Ventolin Pills (Salbutamol)

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What are Ventolin pills?

Ventolin is a drug used to eliminate reversible diseases with bronchial obstruction. The active ingredient is salbutamol. The drug is used in case of bronchial asthma (to relieve seizures) and to prevent attacks of bronchospasm due to allergic reactions and physical exertion. Ventolin is also prescribed for long-term treatment of asthma and other obstructive pulmonary diseases (emphysema, bronchitis).

Dosage and instructions for use

Take this medication orally as directed by your doctor. Dosage is based on your health condition and response to treatment.

Dosage: children older than 12 years – 4-8 mg every 12 hours; maximum dose – 32 mg/day (16 mg every 12 hours); children aged 6 to 12 years – 4 mg every 12 hours, maximum dose – 24 mg/day (12 mg every 12 hours). The pills are swallowed whole, without chewing.

Overdose

Symptoms of an overdose: angina pectoris, tachycardia (with heart rate up to 200 beats per minute), heartbeat, arrhythmia, dizziness, dry mouth, fatigue, headache, hyperglycemia (alternating hypoglycemia), decrease or increase in blood pressure, hypokalemia, insomnia, anxiety, asymptomatic, hypoglycemia, decrease or increase in blood pressure, hypokalemia, insomnia, anxiety, asymptomatic, hypoglycemia, decreased or increased blood pressure, hypokalemia, insomnia, anxiety, nervous tension, convulsions, tremor.

Treatment: symptomatic, gastric lavage and injected cardioselective beta-blockers may be required (with caution).

Side effects

Ventolin pills can cause the following side effects:

• Often: palpitations, tachycardia (during pregnancy – in the mother and in the fetus), headache, tremor, nervous tension;
• Less often: dizziness, insomnia, muscle cramps, nausea, vomiting, sweating;
• Rarely: allergic reactions (urticaria, skin rash, angioedema, paradoxical bronchospasm, erythema multiforme, Stevens-Johnson syndrome, arrhythmia, chest pain, hypokalemia, neuropsychiatric disorders (including psychomotor agitation, disorientation, memory impairment, aggression, panic condition, hallucinations, suicidal attempts, schizophrenia-like disorders, urinary retention.

Contraindications

The use of Ventolin is contraindicated in the following cases:

• hypersensitivity to salbutamol;
• age under 6 years.

With caution: tachyarrhythmia, severe heart failure, hypertension, hyperthyroidism, tachyarrhythmia, pheochromocytoma, pregnancy, lactation, ischemic heart disease (angina, myocardial infarction), myocarditis, valvular heart disease, aortic stenosis, diabetes, epilepsy, convulsions, stenosis of the gastrointestinal tract.

Interactions

• Salbutamol enhances the action of CNS stimulants, tachycardia (in patients with thyrotoxicosis) and the likelihood of developing beats in the presence of cardiac glycosides;
• A single application of salbutamol reduces the concentration of digoxin by 16-22% against the background of 10-day therapy last (it is necessary to monitor the concentration of digoxin in the blood);
• Salbutamol may increase heart rate and blood pressure in patients receiving antihypertensive and antianginal drugs;
• Use with theophylline and other xanthines can increase the likelihood of developing tachyarrhythmias;
• Use with means for inhalation anesthesia can cause severe ventricular arrhythmias;
• MAO inhibitors and tricyclic antidepressants can enhance the effect of salbutamol and lead to a sharp decrease in blood pressure;
• Ventolin is incompatible with non-selective beta-blockers (which must also be considered when using eye forms of beta-blocking agents);
• Simultaneous administration with anticholinergic agents (including inhalants) may contribute to an increase in intraocular pressure;
• Diuretics and GCS enhance the hypokalemic effect of salbutamol.

Precautions

Ventolin pills can be used as one of the components of complex therapy (by prescription). Reduced effectiveness of the medication requires a re-examination of the patient. A sudden deterioration in the patient’s condition while taking the pills can be life-threatening, so it is urgently necessary to seek a doctor’s advice. Be cautious when using thyrotoxicosis. It is necessary to regularly monitor the level of potassium in the blood.

Frequent use of salbutamol can lead to increased bronchospasm, sudden death, so it is necessary to take breaks of several hours (6 hours) between taking the next dose of the drug. The reduction of these intervals can be allowed only in exceptional cases.

If necessary, the drug can be used during lactation (it is not known whether salbutamol penetrates into breast milk).

The bronchodilator can be used during pregnancy since the potential risk of placental hypoxemia to the fetus against the background of uncontrolled asthma greatly exceeds the risk associated with their use. However, you should be cautious when using Ventolin during pregnancy because it can cause tachycardia and hyperglycemia in the mother (especially if she has diabetes) and the fetus, and also cause a delay in labor, reduce blood pressure, acute MK and pulmonary edema.